Citrulline Malate 2:1 1 Kilogram
	Quantity in Basket: None Code: CM1KG Price: $69.99 Shipping Weight: 3.10 pounds
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Mixability Taste   Home Page Store Front   This product has not been evaluated by the FDA and it's not intended to "diagnose, treat, cure or prevent any disease". This unique combination of the amino acid Citrullline and the organic salt Malate offers athletes with a new choice in improving performance and recovery. As an intermediate in the Urea Cycle, Citrulline aids in the removal of endotoxins such as lactic acid and ammonia1. These endotoxins are produced through intense physical activity, protein metabolism, and catabolic states. Endotoxins damage living cells and wreak havoc on athletic performance. What is the difference between 1:1 and 2:1 ratio? In a nut shell. Citrulline is an amino Acid and Malate is an organic salt. There are compounded into Citrulline Malate. Citrulline aids in the removal of endotoxins such as lactic acid and ammonia as well as in arginine production. While the Citrulline part of Citrulline Malate acts to increase NO and to eliminate performance inhibiting metabolic toxins, the Malate part keeps our energy cycle going. They work very well together. The difference between the two is they can be had in this 1:1 and 2:1 versions. With the 1:1 version there is an equal amount of Citrulline and Malate. With the 2:1 version there is 2 parts citrulline with 1 part Malate. Citrulline is really what is making this compound what it is, it just works better with malate compounded with it. Citrulline is more expensive than the malate so there are some manufacturers making this 1:1 version blend. While it's not the ideal ratio it can still be called Citrulline Malate since that is what it is. However using more citrulline is ideal. So therefore the 2:1 ratio is better. In order to get the same amount of Citrulline from 100 grams of the 1:1 version as you would get from 100 grams of the 2:1 version is:   Researches also point to Citrulline as possibly a greater alternative to Arginine for enhancing plasma Arginine2 levels because of Citrullines effects on endogenous Arginine synthesis-meaning that CM may be a superior alternative to Arginine for regulating Nitric Oxide production, growth hormone release, insulin and creatine production. And that's not all, it has also been discovered that supplementing CM at a dose as low as 6 grams a day significantly reduced muscle fatigue, increased ATP production by 34%, and caused a 20% increase in Phosphocreatine recovery after exercise3. What this means is that Citrulline Malate improved aerobic metabolism, cellular energy production, and promoted muscular recovery. Citrulline Malate works by powering ATP (major energy source for muscles) production and by eliminating metabolic pollutants such as Lactic Acid and Ammonia from the blood. Citrulline stimulates energy, boosts the immune system, is metabolized to form L-Arginine and as a result regulate Nitric Oxide production, and detoxifies ammonia, which damages living cells. All exercise results in production of Ammonia. Malate conditions the recycling of lactate and pyruvate and is part of the kreb cycle and can supply instant and sustained energy. While the Citrulline part of Citrulline Malate acts to increase NO and to eliminate performance inhibiting metabolic toxins, the Malate part keeps our energy cycle going. Citrulline Malate also aids in recovery. Subsequent to exercise, muscle levels of creatine phosphate are reduced and it takes some time for levels to be re-elevated. The more Creatine Phosphate your muscles have the stronger and better able to perform they will be. Citrulline Malate stimulates phosphocreatine recovery after exercise, meaning faster recuperation between workouts, and muscles that are primed for growth and your next training session. The minimum dose required for positive effects is 6 grams a day. However some studies have used doses as high as 18 grams a day with remarkable results. I personally experimented with doses as high as 15 grams a day and noticed more profound effect then when I was doing 6 grams a day. Nevertheless, 6 grams a day is enough to notice the ergogenic and health promoting properties of CM. Most of the studies on Citrulline Malate show an increased ability to produce energy through our body's aerobic energy producing cycle. Strength athletes tend to be more concerned with increasing anaerobic energy which is used for explosive movements. Studies clearly show that CM favors the renal (having to do with the kidneys) reabsorption of bicarbonates and protects against metabolic acidosis.1 Very briefly?Anaerobic work involves the breakdown of glycogen. As a result of depleted glycogen stores from anaerobic work, Hydrogen Ions (H+) and lactic Acid in the muscle and blood both increase. This rise in H+ is what causes an increase in acidity in the muscle and leads to the burning sensation of the muscles, fatigue and the failure to maintain high exercise intensity for prolonged periods. It is believed this decrease in ph and increase in acidity is what results in muscular fatigue and the decreased ability for the muscle to contract4,5. Bicarbonates are our body's way of coping with the increased levels of H+ and a decreased pH. Bicarbonates work by stimulating the removal of H+ and lactic acid out of the muscle6. So by aiding in the reabsorption of bicarbonates, CM may also help with increasing the anaerobic threshold and delaying the build up of H+ and lactic acid. For increased athletic performance, here is my list of compounds to stack with CM and what they do: Carnosine: Helps to increase the anaerobic threshold by buffering lactic acid. L-Carnitine: Boosts V02 max, spares glycogen, promotes recovery and stimulates energy production. Creatine: Helps to enhance performance by increasing skeletal muscle creatine phosphate stores and fueling ATP production. Arginine (and various Arginine salts): Neutralizes ammonia and is involved in a variety of enzymes and hormones; insulin, growth hormone, nitric oxide and creatine production. B-Vitamins: Coenzymes involved in energy production. CoQ-10: plays a vital role in production of energy in every cell of the body, aids in circulation, and increases tissue oxygenation. Zinc: not only does it boost testosterone production and boost the immune system, but it is an essential trace element that activates the urea cycle. References: 1. A. Callis, B. Magnan de Bornier, J.J. Serrano, H. Bellet, and R. Saumade. Activity of Citrulline Malate on Acid-Base Balance and Blood Ammonia and Amino Acid Levels 2. Wilkerson JE, Batterson DL, Horvath SM. Exercise induced changes in blood ammonia levels in humans. Eur J Apple Physiol 1977; 37:255-263. 3. Dhanakoti, S. N. et al, Am. J. Physiol. 259:E437-E442, (1990) 4. Bendahan D, Mattei JP, Ghattas B, Confort-Gouny S, Le Guern ME, Cozzone PJ. Br J Sports Med. 2002 Aug; 36(4):282-9. Citrulline/malate promotes aerobic energy production in human exercising muscle.

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